iPTMnet Report for Q9Y3B4 (SF3B6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3B4 / SF3B6_HUMAN
Protein Name Splicing factor 3B subunit 6
Gene Name Name: SF3B6
Synonyms:SAP14,SF3B14,SF3B14A;ORFNames:CGI-110,HSPC175,HT006;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3B4
DAG View
PRO Name splicing factor 3B subunit 6 (human)
Definition A splicing factor 3B subunit 6 that is encoded in the genome of human.
Short Label hSF3B6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3B4 (SF3B6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Sumoylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
K29 Acetylation PhosphoSitePlus   UniProt 19608861
K29 Ubiquitination PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
K41 Acetylation PhosphoSitePlus   UniProt 19608861
K41 Ubiquitination PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
C74 S-Nitrosylation dbSNO 19483679
C83 S-Nitrosylation dbSNO 19483679
Y86 Phosphorylation HPRD   PhosphoSitePlus 15592455
K100 Ubiquitination PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y36 F36 Biomuta DOID:9256 / colorectal cancer [ cosmic ]