iPTMnet Report for Q9Y394 (DHRS7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y394 / DHRS7_HUMAN
Protein Name Dehydrogenase/reductase SDR family member 7 precursor
Gene Name Name: DHRS7
Synonyms:DHRS7A,RETSDR4;ORFNames:CGI-86,UNQ285/PRO3448;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y394
DAG View
PRO Name dehydrogenase/reductase SDR family member 7 (human)
Definition A dehydrogenase/reductase SDR family member 7 that is encoded in the genome of human.
Short Label hDHRS7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y394 (DHRS7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K101 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K321 Methylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T187 Phosphorylation HPRD 18491316
S190 Phosphorylation HPRD 18491316
S206 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K123 N123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S190 I190 Biomuta DOID:363 / uterine cancer [ icgc ]
S206 R206 Biomuta DOID:4159 / skin cancer [ cosmic ]
S322 I322 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S322 G322 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K332 E332 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K332 T332 Biomuta DOID:5041 / esophageal cancer [ cosmic ]