iPTMnet Report for Q9Y314 (NOSIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y314 / NOSIP_HUMAN
Protein Name Nitric oxide synthase-interacting protein
Gene Name Name: NOSIP
ORFNames:CGI-25;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y314
DAG View
PRO Name nitric oxide synthase-interacting protein (human)
Definition A nitric oxide synthase-interacting protein that is encoded in the genome of human.
Short Label hNOSIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y314 (NOSIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Sumoylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
N7 N-Glycosylation GlyGen 24190977
C8 S-Nitrosylation dbSNO 22178444
Y14 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
Y28 Phosphorylation PhosphoSitePlus
T30 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332, 18212344, 20068231
S36 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K41 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
K100 Sumoylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S107 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17287340, 24275569
R112 Methylation PhosphoSitePlus
K117 Sumoylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S119 O-Glycosylation GlyGen 31373491
S123 O-Glycosylation GlyGen 31373491
K132 Ubiquitination PhosphoSitePlus
S135 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T137 Phosphorylation HPRD   phospho.ELM 18669648
S138 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S152 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K157 Sumoylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S166 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T168 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648, 18847512, ...20068231
K172 Sumoylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K175 Sumoylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K178 Sumoylation PhosphoSitePlus
C185 S-Nitrosylation dbSNO 26338901
K190 Sumoylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K257 Sumoylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
R278 Methylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
K289 Sumoylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K294 Sumoylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T15 I15 Biomuta DOID:4159 / skin cancer [ cosmic ]
S26 L26 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K41 N41 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K100 T100 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R112 Q112 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R112 W112 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S123 T123 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K132 Q132 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K132 N132 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S135 L135 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S152 C152 Biomuta [ cosmic ]
C185 R185 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T198 M198 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T216 A216 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]