iPTMnet Report for Q9Y2Z2 (MTO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2Z2 / MTO1_HUMAN
Protein Name Protein MTO1 homolog, mitochondrial precursor
Gene Name Name: MTO1
ORFNames:CGI-02;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2Z2
DAG View
PRO Name protein MTO1 homolog, mitochondrial (human)
Definition A protein MTO1, mitochondrial that is encoded in the genome of human.
Short Label hMTO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2Z2 (MTO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K245 Methylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
Y471 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T480 Phosphorylation PhosphoSitePlus
T481 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
Y488 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K516 Ubiquitination PhosphoSitePlus
K533 Methylation PhosphoSitePlus   UniProt 24129315
K533 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
Y578 Phosphorylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
Y613 Phosphorylation PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y471 Phosphorylation HPRD 18083107
Y488 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
K275 Ubiquitination PhosphoSitePlus
Y285 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y446 Phosphorylation HPRD 18083107
Y463 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K245 R245 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K275 N275 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y463 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T480 S480 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y488 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K555 N555 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T564 A564 Biomuta DOID:3571 / liver cancer [ cosmic ]
K637 N637 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]