iPTMnet Report for Q9Y2X7 (GIT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2X7 / GIT1_HUMAN
Protein Name ARF GTPase-activating protein GIT1
Gene Name Name: GIT1
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2X7
DAG View
PRO Name ARF GTPase-activating protein GIT1 (human)
Definition An ARF GTPase-activating protein GIT1 that is encoded in the genome of human.
Short Label hGIT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2X7 (GIT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation PhosphoSitePlus
S46 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 22893698
S46 Phosphorylation O94806 (PRKD3) neXtProt   PhosphoSitePlus   Signor 22893698
K49 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S134 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
K135 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus   RLIMS-P 22302306
Y321 Phosphorylation P12931 (SRC) PhosphoSitePlus 22302306
Y321 Phosphorylation Q05397 (PTK2) PhosphoSitePlus 22302306
K358 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S362 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18669648, 19690332
T364 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S370 Phosphorylation PhosphoSitePlus   UniProt 23186163
S373 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S375 Phosphorylation PhosphoSitePlus   UniProt 19690332
Y383 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   UniProt 18669648, 19690332
S385 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18088087, 19690332, ...20068231
S388 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18088087, 17081983, ...15302935, 18318008, 18669648, 24275569, 23186163, 19690332, 20068231
T392 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S410 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
S413 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S414 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S417 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S448 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus   UniProt 24275569
T491 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus   UniProt 23186163
T499 Phosphorylation PhosphoSitePlus
S508 Phosphorylation phospho.ELM   PhosphoSitePlus 16246726
S508 Phosphorylation Q13153 (PAK1) PhosphoSitePlus 16246726
Y510 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
K517 Methylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Y545 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 19690332
S546 Phosphorylation PhosphoSitePlus
Y554 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455
S561 O-Glycosylation GlyGen 34019948, 35132862, 28657654
S561 Phosphorylation PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S575 O-Glycosylation GlyGen 34019948, 35132862, 28657654
S575 Phosphorylation PhosphoSitePlus
S577 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
S592 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 17081983, 18669648, ...24275569, 23186163, 19690332
S596 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
Y598 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18088087
T601 Phosphorylation PhosphoSitePlus   UniProt 19690332
K613 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
C674 S-Nitrosylation dbSNO 26338901
K677 Acetylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus 16797488
S700 Phosphorylation Q13153 (PAK1) PhosphoSitePlus 16797488
T753 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation HPRD 17287340
Y246 Phosphorylation HPRD 16825424
Y284 Phosphorylation HPRD 16825424
S359 Phosphorylation HPRD 17081983
S361 Phosphorylation HPRD 19415658, 20068231
S362 Phosphorylation HPRD 19413330, 16825424, 18767875, ...20058876, 19651622, 18669648, 19415658, 20068231
T364 Phosphorylation HPRD 17322306, 19651622, 18669648, ...20068231
S373 Phosphorylation HPRD 18669648
S375 Phosphorylation HPRD 18452278
Y383 Phosphorylation HPRD 19413330, 19651622, 18669648, ...16825424, 18452278
S385 Phosphorylation HPRD 18088087, 16825424, 18452278, ...19651622, 18669648, 19415658, 20068231
S388 Phosphorylation HPRD 19413330, 18088087, 16825424, ...15302935, 18452278, 19651622, 18510355, 18669648, 20166139, 19415658, 20068231
T392 Phosphorylation HPRD 20166139, 18669648, 16825424, ...18452278
S410 Phosphorylation HPRD 18669648, 20058876, 16825424, ...20068231
S413 Phosphorylation HPRD 18669648, 18452278
S414 Phosphorylation HPRD 18669648
S417 Phosphorylation HPRD 18669648
T480 Phosphorylation HPRD 16825424
T491 Phosphorylation HPRD 20068231
T499 Phosphorylation HPRD 20068231
Y510 Phosphorylation HPRD 16825424, 20068231
S536 Phosphorylation HPRD 16825424
T537 Phosphorylation HPRD 16825424
Y545 Phosphorylation HPRD 17016520, 17389395, 16825424, ...20068231, 16497976
S546 Phosphorylation HPRD 16825424, 20068231
Y554 Phosphorylation HPRD 16825424, 16497976
S563 Phosphorylation HPRD 16825424
S588 Phosphorylation HPRD 20068231
S592 Phosphorylation HPRD 19413330, 18088087, 16825424, ...18452278, 19651622, 18669648, 20068231
S596 Phosphorylation HPRD 19651622, 18669648, 16825424, ...20068231
Y598 Phosphorylation HPRD 19413330, 16083285, 18088087, ...16825424, 18669648, 20068231
T601 Phosphorylation HPRD 16825424
S630 Phosphorylation HPRD 16825424
Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation HPRD 17287340
Y246 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
S368 Phosphorylation HPRD 17081983
S370 Phosphorylation HPRD 19415658, 20068231
S371 Phosphorylation HPRD   PhosphoSitePlus 19413330, 17322306, 18767875, ...20058876, 19651622, 18669648, 19415658, 20068231
T373 Phosphorylation HPRD 17322306, 19651622, 18669648, ...20068231
S382 Phosphorylation HPRD   PhosphoSitePlus 18669648
S384 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y392 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18669648, 19651622, ...18452278
S394 Phosphorylation HPRD   PhosphoSitePlus 18088087, 17081983, 18452278, ...19651622, 18669648, 19415658, 20068231
S397 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18088087, 17081983, ...18452278, 19651622, 18510355, 18669648, 20166139, 19415658, 20068231
T401 Phosphorylation HPRD   PhosphoSitePlus 20166139, 18669648, 18452278
S419 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20058876, 20068231
S422 Phosphorylation HPRD   PhosphoSitePlus 18669648, 18452278
S423 Phosphorylation HPRD   PhosphoSitePlus 18669648
S426 Phosphorylation HPRD 18669648
S457 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
T500 Phosphorylation HPRD 20068231
S507 Phosphorylation PhosphoSitePlus
T508 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y519 Phosphorylation HPRD   PhosphoSitePlus 20068231
S545 Phosphorylation PhosphoSitePlus
T546 Phosphorylation PhosphoSitePlus
Y554 Phosphorylation HPRD   PhosphoSitePlus 17016520, 17389395, 15592455, ...20068231, 16497976
S555 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y563 Phosphorylation HPRD   PhosphoSitePlus 15592455, 16497976
S572 Phosphorylation PhosphoSitePlus
S597 Phosphorylation HPRD 20068231
S601 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18088087, 17081983, ...18452278, 19651622, 18669648, 20068231
S605 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648, 20068231
Y607 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18088087, 17081983, ...18669648, 20068231
T610 Phosphorylation HPRD   PhosphoSitePlus 17081983
S639 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
T765 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047536 (hGIT1/Phos:2) pY383 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9Y2X7 (GIT1) Y321 Q05397 (PTK2) unknown eFIP 22302306