iPTMnet Report for Q9Y2W6 (TDRKH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2W6 / TDRKH_HUMAN
Protein Name Tudor and KH domain-containing protein
Gene Name Name: TDRKH
Synonyms:TDRD2;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2W6
DAG View
PRO Name tudor and KH domain-containing protein (human)
Definition A tudor and KH domain-containing protein that is encoded in the genome of human.
Short Label hTDRKH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2W6 (TDRKH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y31 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus   UniProt 25621951
K76 Ubiquitination UniProt 25621951
T90 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus   UniProt 25621951
K112 Ubiquitination PhosphoSitePlus   UniProt 25621951
R142 Methylation PhosphoSitePlus
K152 Ubiquitination UniProt 25621951
K162 Ubiquitination PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus   UniProt 25621951
K181 Ubiquitination PhosphoSitePlus   UniProt 25621951
K187 Ubiquitination PhosphoSitePlus   UniProt 25621951
K193 Ubiquitination PhosphoSitePlus   UniProt 25621951
R201 Methylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
K256 Ubiquitination UniProt 25621951
K267 Ubiquitination UniProt 25621951
S270 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus   UniProt 23186163
S282 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
K478 Acetylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K479 Ubiquitination UniProt 25621951
K510 Ubiquitination PhosphoSitePlus   UniProt 25621951
S519 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K529 Ubiquitination UniProt 25621951
Site PTM Type PTM Enzyme Score Source PMID
T159 Phosphorylation HPRD 17322306
Site PTM Type PTM Enzyme Score Source PMID
T114 Phosphorylation HPRD 17322306


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K112 E112 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R142 K142 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S171 T171 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K175 T175 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R201 W201 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S270 F270 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S282 P282 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K449 T449 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y470 F470 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y470 N470 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K510 N510 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K529 N529 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]