iPTMnet Report for Q9Y2W2 (WBP11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2W2 / WBP11_HUMAN
Protein Name WW domain-binding protein 11
Gene Name Name: WBP11
Synonyms:NPWBP,SIPP1,SNP70;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2W2
DAG View
PRO Name WW domain-binding protein 11 (human)
Definition A WW domain-binding protein 11 that is encoded in the genome of human.
Short Label hWBP11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2W2 (WBP11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 O-Glycosylation GlyGen 30620550
K13 Acetylation PhosphoSitePlus   UniProt 19608861
K13 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
Y114 Phosphorylation HPRD   PhosphoSitePlus 20068231
K117 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
K169 Methylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
R178 Methylation PhosphoSitePlus
S181 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19690332, 18212344
R192 Methylation PhosphoSitePlus   UniProt 24129315
Y236 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
S237 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...17081983, 18767875, 18452278, 19651622, 18669648, 18707149, 19415658, 20068231
S250 Phosphorylation HPRD   PhosphoSitePlus 18452278
S251 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
T252 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
S253 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
S270 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
T271 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
S274 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
T276 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
S279 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17081983, ...18452278
S283 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17081983, ...18452278
K319 Acetylation PhosphoSitePlus
T328 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18491316
S353 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18669648, 19690332
S361 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18669648, 24275569, 19690332
S364 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18669648, 24275569, 19690332
R485 Methylation PhosphoSitePlus
R508 Methylation PhosphoSitePlus
K565 Acetylation PhosphoSitePlus
R577 Methylation PhosphoSitePlus
T593 Phosphorylation PhosphoSitePlus
S600 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18452278
S604 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K610 Ubiquitination PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
S615 O-Glycosylation GlyGen 30444036, 28510447, 34019948, ...33214551, 35254053
S615 Phosphorylation PhosphoSitePlus
S622 O-Glycosylation GlyGen 30444036, 28510447, 34019948, ...33214551, 35254053
K626 Ubiquitination PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K117 M117 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R178 Q178 Biomuta DOID:363 / uterine cancer [ icgc ]
R178 W178 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S181 C181 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R192 H192 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S237 T237 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S274 N274 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K319 N319 Biomuta DOID:1612 / breast cancer [ cosmic ]
S364 C364 Biomuta DOID:1324 / lung cancer [ cosmic ]
R485 H485 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R577 Q577 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
K610 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K614 R614 Biomuta DOID:10534 / stomach cancer [ cosmic ]