iPTMnet Report for Q9Y2V2 (CARHSP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2V2 / CHSP1_HUMAN
Protein Name Calcium-regulated heat-stable protein 1
Gene Name Name: CARHSP1
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2V2
DAG View
PRO Name calcium-regulated heat-stable protein 1 (human)
Definition A calcium-regulated heat-stable protein 1 that is encoded in the genome of human.
Short Label hCARHSP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2V2 (CARHSP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692
S2 Phosphorylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
T23 Phosphorylation P06493 (CDK1) HPRD   PhosphoSitePlus 18234856, 20068231
S26 Phosphorylation HPRD   PhosphoSitePlus 20068231
S30 Phosphorylation Q92630 (DYRK2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19477163, 19651622, 24275569, ...23186163, 17081983, 17322306, 18669648, 15910284, 17287340, 20068231
S32 Phosphorylation Q92630 (DYRK2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19477163, 23186163, 15910284, ...17322306, 18669648, 20068231, 24275569, 17287340, 19651622, 17081983
S41 Phosphorylation Q92630 (DYRK2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 16964243, 19477163, 18691976, ...21406692, 23186163, 18212344, 21177848, 24275569, 19413330, 18088087, 18220336, 18767875, 20058876, 19651622, 17287340, 17081983, 19664994, 19664995, 17322306, 18669648, 15910284, 20068231
T45 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18767875, ...19651622, 18669648, 20068231
T48 Phosphorylation PhosphoSitePlus
R49 Methylation PhosphoSitePlus
T50 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15302935, 20068231
S52 Phosphorylation P31749 (AKT1) , Q15418 (RPS6KA1) , O00141 (SGK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19477163, 21406692, 16083285, ...18088087, 16964243, 18212344, 18767875, 19413330, 19664995, 19651622, 17322306, 18669648, 15910284, 20058876, 20166139, 23186163, 19415658, 20068231, 24275569
T54 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y63 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
C67 S-Nitrosylation dbSNO 26338901
K68 Acetylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
C69 S-Nitrosylation dbSNO 26338901
C71 S-Nitrosylation dbSNO 26338901
K74 Ubiquitination PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K120 Acetylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S146 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 18220336
S147 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 18220336


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T48 M48 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S52 L52 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
C67 F67 Biomuta DOID:4159 / skin cancer [ cosmic ]