Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2U5 / M3K2_HUMAN
Protein Name Mitogen-activated protein kinase kinase kinase 2
Gene Name Name: MAP3K2
Synonyms:MAPKKK2,MEKK2;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2U5
DAG View
PRO Name mitogen-activated protein kinase kinase kinase 2 (human)
Definition A mitogen-activated protein kinase kinase kinase 2 that is encoded in the genome of human.
Short Label hMAP3K2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2U5 (MAP3K2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 18220336
S109 Phosphorylation PhosphoSitePlus
S153 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 18212344, ...19369195, 18767875, 17322306, 18669648, 20166139, 20068231
T158 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231
S159 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S163 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18220336, 19651622, ...18669648, 20166139, 20068231
S164 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18088087, 18220336, 17192257, ...19651622, 18669648, 18707149, 20068231
Y169 Phosphorylation PhosphoSitePlus
S239 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 18669648, ...20166139, 19690332
Y240 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K260 Methylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus   RLIMS-P 23963453
T290 Phosphorylation PhosphoSitePlus
S297 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18220336
S300 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S302 Phosphorylation PhosphoSitePlus
T310 Phosphorylation HPRD 18691976
S311 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163
S312 Phosphorylation HPRD   PhosphoSitePlus 18691976
S314 Phosphorylation HPRD   PhosphoSitePlus 18691976
S315 Phosphorylation HPRD   PhosphoSitePlus 18691976
S331 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19369195, ...18669648, 24275569, 19690332
T337 Phosphorylation PhosphoSitePlus
S344 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19369195, 18691976, 19651622, ...18669648, 19690332
S347 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18669648
S349 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18691976
K360 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
T516 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus


Q9Y2U5 (MAP3K2) as PTM Enzyme



Substrate Site Score Source PMID
O14733 (MAP2K7) S271 neXtProt 10347227, 10713157
O14733 (MAP2K7) T275 neXtProt 10347227, 10713157