iPTMnet Report for Q9Y2T3 (GDA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2T3 / GUAD_HUMAN
Protein Name Guanine deaminase
Gene Name Name: GDA
Synonyms:KIAA1258;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2T3
DAG View
PRO Name guanine deaminase (human)
Definition A guanine deaminase that is encoded in the genome of human.
Short Label hGDA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2T3 (GDA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K41 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K201 T201 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K231 I231 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y255 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K259 T259 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K267 I267 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S453 L453 Biomuta DOID:4159 / skin cancer [ cosmic ]
S453 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]