iPTMnet Report for Q9Y2Q1 (ZNF257)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2Q1 / ZN257_HUMAN
Protein Name Zinc finger protein 257
Gene Name Name: ZNF257
Synonyms:BMZF4;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2Q1
DAG View
PRO Name zinc finger protein 257 (human)
Definition A zinc finger protein 257 that is encoded in the genome of human.
Short Label hZNF257
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2Q1 (ZNF257) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T224 Phosphorylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K230 Sumoylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K258 Sumoylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
K317 Sumoylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K373 Sumoylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K432 Acetylation PhosphoSitePlus
K432 Sumoylation PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
K460 Acetylation PhosphoSitePlus
K460 Sumoylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K488 Acetylation PhosphoSitePlus
K488 Sumoylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
T510 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K516 Acetylation PhosphoSitePlus
K516 Sumoylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
T531 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T224 I224 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K227 I227 Biomuta DOID:3571 / liver cancer [ cosmic ]
K230 Q230 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K258 T258 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K258 N258 Biomuta DOID:4362 / cervical cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
T311 S311 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T311 I311 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K314 R314 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y316 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y316 H316 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K317 Q317 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K317 R317 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T339 I339 Biomuta DOID:3571 / liver cancer [ cosmic ]
K351 E351 Biomuta DOID:4159 / skin cancer [ cosmic ]
K373 Q373 Biomuta DOID:4159 / skin cancer [ cosmic ]
K379 E379 Biomuta DOID:363 / uterine cancer [ icgc ]
K422 N422 Biomuta DOID:363 / uterine cancer [ icgc ]
K422 E422 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K422 R422 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K422 T422 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K450 T450 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K450 R450 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K460 N460 Biomuta DOID:1324 / lung cancer [ cosmic ]
K494 E494 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K494 N494 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]