iPTMnet Report for Q9Y2N7 (HIF3A)
Protein Information
| UniProt AC / UniProt ID | Q9Y2N7 / HIF3A_HUMAN |
| Protein Name | Hypoxia-inducible factor 3-alpha |
| Gene Name | Name: HIF3A Synonyms:BHLHE17,MOP7,PASD7; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y2N7 |
| PRO Name | hypoxia-inducible factor 3-alpha (human) |
| Definition | A hypoxia-inducible factor 3-alpha that is encoded in the genome of human. |
| Short Label | hHIF3A |
| Category | organism-gene |
DAG ViewQ9Y2N7 (HIF3A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T12 | Phosphorylation | score3 | RLIMS-P+ Signor | 27551449 | ||
| T12 | Phosphorylation | Q9BXM7 (PINK1) | score3 | RLIMS-P+ Signor | 27551449 | |
| S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S398 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K467 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 12538644 | ||
| K570 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 12538644 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S28 | N28 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y35 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T173 | I173 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S396 | F396 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S398 | N398 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] |
