iPTMnet Report for Q9Y2L6 (FRMD4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2L6 / FRM4B_HUMAN
Protein Name FERM domain-containing protein 4B
Gene Name Name: FRMD4B
Synonyms:GRSP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2L6
DAG View
PRO Name FERM domain-containing protein 4B (human)
Definition A FERM domain-containing protein 4B that is encoded in the genome of human.
Short Label hFRMD4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2L6 (FRMD4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K95 Acetylation PhosphoSitePlus
K263 Acetylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
K561 Acetylation PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
S608 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087
S628 Phosphorylation PhosphoSitePlus
T636 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
R656 Methylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
T666 Phosphorylation PhosphoSitePlus
R671 Methylation PhosphoSitePlus
Y674 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
S856 Phosphorylation PhosphoSitePlus
Y870 Phosphorylation PhosphoSitePlus
T872 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus   UniProt 18088087
S926 Phosphorylation PhosphoSitePlus
S940 Phosphorylation PhosphoSitePlus
T973 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S604 Phosphorylation HPRD 18088087
S608 Phosphorylation HPRD 18088087
S628 Phosphorylation HPRD 18088087
S915 Phosphorylation HPRD 18088087


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T568 I568 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S628 F628 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S628 C628 Biomuta DOID:263 / kidney cancer [ cosmic ]
T636 N636 Biomuta [ cosmic ]
S648 G648 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R656 W656 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R656 Q656 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
T666 M666 Biomuta DOID:1319 / brain cancer [ cosmic ]
R671 Q671 Biomuta DOID:9256 / colorectal cancer [ cosmic ]