iPTMnet Report for Q9Y2L5 (TRAPPC8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2L5 / TPPC8_HUMAN
Protein Name Trafficking protein particle complex subunit 8
Gene Name Name: TRAPPC8
Synonyms:KIAA1012;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2L5
DAG View
PRO Name trafficking protein particle complex subunit 8 (human)
Definition A trafficking protein particle complex subunit 8 that is encoded in the genome of human.
Short Label hTRAPPC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2L5 (TRAPPC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
T232 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S279 Phosphorylation PhosphoSitePlus   UniProt 23186163
K288 Ubiquitination PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus   UniProt 23186163
S311 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
C505 Methylation IEDB 31844290
K514 Ubiquitination PhosphoSitePlus
Y560 Phosphorylation PhosphoSitePlus
K573 Acetylation PhosphoSitePlus
K577 Acetylation PhosphoSitePlus
K578 Acetylation PhosphoSitePlus
Y584 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K594 Ubiquitination PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
K723 Ubiquitination PhosphoSitePlus
K783 Ubiquitination PhosphoSitePlus
Y841 Phosphorylation PhosphoSitePlus
T851 Phosphorylation PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
K942 Ubiquitination PhosphoSitePlus
T964 Phosphorylation PhosphoSitePlus
T968 Phosphorylation PhosphoSitePlus
S971 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S973 Phosphorylation PhosphoSitePlus
C1074 Methylation IEDB 31844290
K1136 Ubiquitination PhosphoSitePlus
K1147 Acetylation PhosphoSitePlus
K1155 Acetylation PhosphoSitePlus
K1209 Ubiquitination PhosphoSitePlus
K1220 Ubiquitination PhosphoSitePlus
K1278 Ubiquitination PhosphoSitePlus
K1288 Ubiquitination PhosphoSitePlus
K1311 Ubiquitination PhosphoSitePlus
N1340 N-Glycosylation GlyGen 29741879, 29671580
S1342 Phosphorylation PhosphoSitePlus
K1381 Ubiquitination PhosphoSitePlus
S1433 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S273 Phosphorylation HPRD 19651622, 15345747
Y584 Phosphorylation HPRD 18083107
S971 Phosphorylation HPRD 18669648
N1340 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K69 R69 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K69 N69 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y179 H179 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K183 M183 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K514 T514 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K573 N573 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S973 P973 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1147 N1147 Biomuta DOID:1319 / brain cancer [ icgc ]
K1381 I1381 Biomuta DOID:4606 / bile duct cancer [ cosmic ]