iPTMnet Report for Q9Y2K2 (SIK3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2K2 / SIK3_HUMAN
Protein Name Serine/threonine-protein kinase SIK3
Gene Name Name: SIK3
Synonyms:KIAA0999;ORFNames:L19;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2K2
DAG View
PRO Name serine/threonine-protein kinase SIK3 (human)
Definition A serine/threonine-protein kinase QSK that is encoded in the genome of human.
Short Label hSIK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2K2 (SIK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus   UniProt 19369195
K74 Ubiquitination PhosphoSitePlus
K81 Acetylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
E113 Phosphorylation UniProt 19690332
K190 Ubiquitination PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus   Signor   UniProt 19369195, 23186163, 30232230, ...14976552
T221 Phosphorylation Q15831 (STK11) Signor 14976552
K279 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus   UniProt 29211348, 23186163, 24275569
T536 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
R569 Methylation IEDB 27503676
S591 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus   UniProt 19369195, 18669648, 23186163, ...24275569
S631 Phosphorylation PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
Y662 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus
S866 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
S869 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus   UniProt 24275569
R986 Methylation PhosphoSitePlus
Y1015 Phosphorylation PhosphoSitePlus
S1094 Phosphorylation PhosphoSitePlus
S1169 Phosphorylation PhosphoSitePlus
T1217 Phosphorylation PhosphoSitePlus
Y1225 Phosphorylation PhosphoSitePlus
Y1307 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T113 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K81 Acetylation PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
R519 Methylation PhosphoSitePlus
R521 Methylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
R581 Methylation PhosphoSitePlus
T1157 Phosphorylation PhosphoSitePlus


Q9Y2K2 (SIK3) as PTM Enzyme



Substrate Site Score Source PMID
Q53ET0 (CRTC2) S70 HPRD   Signor 16306228, 18669648
Q53ET0 (CRTC2) S171 HPRD   Signor 16306228, 18669648, 15454081
Q53ET0 (CRTC2) S348 HPRD   Signor 16306228