iPTMnet Report for Q9Y2J2 (EPB41L3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2J2 / E41L3_HUMAN
Protein Name Band 4.1-like protein 3
Gene Name Name: EPB41L3
Synonyms:DAL1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2J2
DAG View
PRO Name band 4.1-like protein 3 (human)
Definition A band 4.1-like protein 3 that is encoded in the genome of human.
Short Label hEPB41L3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2J2 (EPB41L3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
T2 Acetylation UniProt 19413330
T2 Phosphorylation PhosphoSitePlus
T3 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation IEDB 35494241
S361 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
K405 Acetylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
Y408 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus   UniProt 24275569
S443 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus   UniProt 21406692
T462 Phosphorylation PhosphoSitePlus
T466 Phosphorylation PhosphoSitePlus 18847512
T466 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T467 Phosphorylation PhosphoSitePlus 18847512
T467 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T469 Phosphorylation PhosphoSitePlus   UniProt 21406692
K487 Ubiquitination PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
T704 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
S708 Phosphorylation PhosphoSitePlus
N734 N-Glycosylation GlyGen 29741879
S736 Phosphorylation PhosphoSitePlus
K739 Methylation PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
T761 Phosphorylation PhosphoSitePlus
S762 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
S867 Phosphorylation PhosphoSitePlus
Y872 Phosphorylation PhosphoSitePlus
T953 O-Glycosylation GlyGen 33214551, 35138101, 34725712, ...34019948, 32119511, 28657654
S957 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus 18847512
S960 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S962 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18847512, 16964243, 24275569
S962 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T980 O-Glycosylation GlyGen 33214551, 35138101, 34725712, ...34019948, 32119511, 28657654
Y987 Phosphorylation PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus
T1025 Phosphorylation PhosphoSitePlus
K1027 Ubiquitination PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
K1061 Ubiquitination PhosphoSitePlus
S1068 Phosphorylation PhosphoSitePlus
T1081 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation HPRD 19413330
S5 Phosphorylation HPRD 19413330, 19415658
S7 Phosphorylation HPRD 19413330, 19415658
S9 Phosphorylation HPRD 19413330
S11 Phosphorylation HPRD 18510355
S88 Phosphorylation HPRD 18077418
S91 Phosphorylation HPRD 18077418
S92 Phosphorylation HPRD 18077418
S273 Phosphorylation HPRD 20058876
S409 Phosphorylation HPRD 17081983
S420 Phosphorylation HPRD 20166139
S460 Phosphorylation HPRD 19413330, 15345747, 18077418, ...19664994, 20058876
T469 Phosphorylation HPRD 19413330, 15345747, 19664994, ...19415658, 20058876
T492 Phosphorylation HPRD 19415658
S708 Phosphorylation HPRD 18510355, 15345747
S746 Phosphorylation HPRD 19415658
S760 Phosphorylation HPRD 20068231
S762 Phosphorylation HPRD 18088087, 19415658
S962 Phosphorylation HPRD 19413330, 16964243, 20058876, ...19664994, 15345747, 19415658
Site PTM Type PTM Enzyme Score Source PMID
S420 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
Y471 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
T543 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 M2 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S7 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y79 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S88 C88 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S93 R93 Biomuta DOID:3571 / liver cancer [ cosmic ]
S93 G93 Biomuta DOID:1324 / lung cancer [ cosmic ]
K128 Q128 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K128 R128 Biomuta DOID:1324 / lung cancer [ cosmic ]
K162 N162 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T278 A278 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T278 M278 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S361 N361 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y408 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T466 I466 Biomuta DOID:4159 / skin cancer [ cosmic ]
T468 I468 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T469 N469 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K475 E475 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T492 M492 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S495 L495 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
T535 A535 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T535 I535 Biomuta DOID:4159 / skin cancer [ cosmic ]
T543 S543 Biomuta DOID:1319 / brain cancer [ cosmic ]
T704 A704 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T704 I704 Biomuta DOID:4159 / skin cancer [ cosmic ]
N734 S734 Biomuta DOID:4159 / skin cancer [ cosmic ]
S736 R736 Biomuta DOID:3571 / liver cancer [ cosmic ]
S736 N736 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S746 A746 Biomuta DOID:363 / uterine cancer [ icgc ]
K757 N757 Biomuta DOID:3571 / liver cancer [ cosmic ]
K757 R757 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S760 T760 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S760 Y760 Biomuta DOID:1324 / lung cancer [ cosmic ]
T761 I761 Biomuta [ cosmic ]
T953 M953 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S962 L962 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y987 C987 Biomuta DOID:3571 / liver cancer [ cosmic, icgc, tcga ]
K1061 R1061 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K1061 T1061 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
S1068 L1068 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1068 T1068 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]