iPTMnet Report for Q9Y2E5 (MAN2B2)
Protein Information
| UniProt AC / UniProt ID | Q9Y2E5 / MA2B2_HUMAN |
| Protein Name | Epididymis-specific alpha-mannosidase precursor |
| Gene Name | Name: MAN2B2 Synonyms:KIAA0935; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y2E5 |
| PRO Name | epididymis-specific alpha-mannosidase (human) |
| Definition | An epididymis-specific alpha-mannosidase that is encoded in the genome of human. |
| Short Label | hMAN2B2 |
| Category | organism-gene |
DAG ViewQ9Y2E5 (MAN2B2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N226 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N336 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 29391424, ... | ||
| Y435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N516 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218 | ||
| N748 | N-Glycosylation | score1 | GlyGen | 23090970, 29391424, 24190977 | ||
| K768 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N890 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| S984 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S225 | F225 | Biomuta | [ cosmic ] | |
| N748 | S748 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
