iPTMnet Report for Q9Y2D8 (SSX2IP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2D8 / ADIP_HUMAN
Protein Name Afadin- and alpha-actinin-binding protein
Gene Name Name: SSX2IP
Synonyms:KIAA0923;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2D8
DAG View
PRO Name afadin- and alpha-actinin-binding protein (human)
Definition An afadin- and alpha-actinin-binding protein that is encoded in the genome of human.
Short Label hSSX2IP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2D8 (SSX2IP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus   UniProt 20068231
S293 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 20068231, 16565220
S306 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S312 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S325 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S341 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
S536 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S540 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S542 Phosphorylation PhosphoSitePlus   UniProt 23186163
T543 Phosphorylation PhosphoSitePlus
K582 Acetylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S290 Phosphorylation HPRD 20068231
S293 Phosphorylation HPRD 19691289, 20068231, 16565220
S306 Phosphorylation HPRD 18669648
S312 Phosphorylation HPRD 19651622, 18669648, 19664994, ...20068231, 18452278
S325 Phosphorylation HPRD 16565220
T339 Phosphorylation HPRD 19007248, 19691289
S341 Phosphorylation HPRD 19007248, 20068231, 19691289
S452 Phosphorylation HPRD 19691289, 20068231
T454 Phosphorylation HPRD 19691289, 20068231
S536 Phosphorylation HPRD 18669648, 20068231
S540 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
S542 Phosphorylation HPRD 20068231
T565 Phosphorylation HPRD 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K182 T182 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y231 C231 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K257 N257 Biomuta DOID:363 / uterine cancer [ icgc ]
S290 Y290 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S290 F290 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S293 T293 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S341 N341 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S341 I341 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K429 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T454 I454 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T565 N565 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]