iPTMnet Report for Q9Y2D1 (ATF5)
Protein Information
UniProt AC / UniProt ID | Q9Y2D1 / ATF5_HUMAN |
Protein Name | Cyclic AMP-dependent transcription factor ATF-5 |
Gene Name | Name: ATF5 Synonyms:ATFX; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y2D1 |
PRO Name | cyclic AMP-dependent transcription factor ATF-5 (human) |
Definition | A cyclic AMP-dependent transcription factor ATF-5 that is encoded in the genome of human. |
Short Label | hATF5 |
Category | organism-gene |
Q9Y2D1 (ATF5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K29 | Acetylation | score1 | PhosphoSitePlus | |||
K106 | Sumoylation | score1 | PhosphoSitePlus | |||
K107 | Sumoylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y225 | Phosphorylation | score1 | PhosphoSitePlus | |||
K229 | Ubiquitination | score1 | PhosphoSitePlus | |||
S256 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K29 | R29 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
K106 | M106 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S220 | L220 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S256 | F256 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |