iPTMnet Report for Q9Y2A7 (NCKAP1)
Protein Information
UniProt AC / UniProt ID | Q9Y2A7 / NCKP1_HUMAN |
Protein Name | Nck-associated protein 1 |
Gene Name | Name: NCKAP1 Synonyms:HEM2,KIAA0587,NAP1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y2A7 |
PRO Name | Nck-associated protein 1 (human) |
Definition | A Nck-associated protein 1 that is encoded in the genome of human. |
Short Label | hNCKAP1 |
Category | organism-gene |
Q9Y2A7 (NCKAP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330 | ||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
R23 | Methylation | score1 | PhosphoSitePlus | |||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
K63 | Acetylation | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
T142 | Phosphorylation | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
S171 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y175 | Phosphorylation | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
K201 | Acetylation | score1 | PhosphoSitePlus | |||
S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
S528 | Phosphorylation | score1 | PhosphoSitePlus | |||
C543 | Methylation | score1 | IEDB | 31844290 | ||
K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
K635 | Ubiquitination | score1 | PhosphoSitePlus | |||
S638 | Phosphorylation | score1 | PhosphoSitePlus | |||
K643 | Ubiquitination | score1 | PhosphoSitePlus | |||
K644 | Ubiquitination | score1 | PhosphoSitePlus | |||
S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
K651 | Ubiquitination | score1 | PhosphoSitePlus | |||
S664 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y691 | Phosphorylation | score1 | PhosphoSitePlus | |||
S719 | Phosphorylation | score1 | PhosphoSitePlus | |||
S801 | Phosphorylation | score1 | PhosphoSitePlus | |||
S838 | Phosphorylation | score1 | PhosphoSitePlus | |||
S840 | Phosphorylation | score1 | PhosphoSitePlus | |||
S852 | Phosphorylation | score1 | PhosphoSitePlus | |||
K886 | Ubiquitination | score1 | PhosphoSitePlus | |||
K895 | Ubiquitination | score1 | PhosphoSitePlus | |||
S899 | Phosphorylation | score1 | PhosphoSitePlus | |||
S902 | Phosphorylation | score1 | PhosphoSitePlus | |||
T908 | Phosphorylation | score1 | PhosphoSitePlus | |||
C969 | Methylation | score1 | IEDB | 31844290 | ||
T1045 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1050 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1065 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1075 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1116 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1120 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1123 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1126 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34019948, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T141 | R141 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
T142 | A142 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K551 | N551 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
K635 | E635 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K643 | N643 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S719 | P719 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S902 | G902 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T908 | A908 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
C969 | F969 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K1075 | E1075 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y1116 | H1116 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y1116 | C1116 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |