Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y287 / ITM2B_HUMAN
Protein Name Integral membrane protein 2B
Gene Name Name: ITM2B
Synonyms:BRI,BRI2;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y287
DAG View
PRO Name integral membrane protein 2B (human)
Definition An integral membrane protein 2B that is encoded in the genome of human.
Short Label hITM2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y287 (ITM2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
N170 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 21752865, ...24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y76 C76 Biomuta DOID:1324 / lung cancer [ tcga ]
N170 I170 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
N170 D170 Biomuta DOID:1324 / lung cancer [ cosmic ]