iPTMnet Report for Q9Y285 (FARSA)
Protein Information
UniProt AC / UniProt ID | Q9Y285 / SYFA_HUMAN |
Protein Name | Phenylalanine--tRNA ligase alpha subunit |
Gene Name | Name: FARSA Synonyms:FARS,FARSL,FARSLA; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y285 |
PRO Name | phenylalanine--tRNA ligase alpha subunit (human) |
Definition | A eukaryotic-type phenylalanine--tRNA ligase alpha subunit that is encoded in the genome of human. |
Short Label | hFARSA |
Category | organism-gene |
Q9Y285 (FARSA) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895, ... | ||
R12 | Methylation | score1 | PhosphoSitePlus | |||
S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
K117 | Acetylation | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
R124 | Methylation | score1 | PhosphoSitePlus | |||
R144 | Methylation | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
K163 | Ubiquitination | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
T190 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S193 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y210 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y292 | Phosphorylation | score1 | PhosphoSitePlus | |||
K297 | Acetylation | score1 | PhosphoSitePlus | |||
T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
S301 | Phosphorylation | Q13535 (ATR) | score1 | PhosphoSitePlus | 18077418 | |
Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y310 | Phosphorylation | score1 | PhosphoSitePlus | |||
K311 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K311 | Sumoylation | score1 | PhosphoSitePlus | |||
K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
K342 | Ubiquitination | score1 | PhosphoSitePlus | |||
K343 | Ubiquitination | score1 | PhosphoSitePlus | |||
T346 | Phosphorylation | score1 | PhosphoSitePlus | |||
K349 | Acetylation | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y350 | Phosphorylation | score1 | PhosphoSitePlus | |||
R355 | Methylation | score1 | PhosphoSitePlus | |||
K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
K468 | Ubiquitination | score1 | PhosphoSitePlus | |||
K481 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y488 | Phosphorylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
C493 | Methylation | score1 | IEDB | 31844290 | ||
T504 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S43 | R43 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K101 | E101 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R124 | Q124 | Biomuta | DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
R144 | W144 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
R144 | L144 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
R144 | Q144 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S184 | R184 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K297 | N297 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S307 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
R355 | H355 | Biomuta | [ cosmic ] |