iPTMnet Report for Q9Y283 (INVS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y283 / INVS_HUMAN
Protein Name Inversin
Gene Name Name: INVS
Synonyms:INV,NPHP2;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y283
DAG View
PRO Name inversin (human)
Definition An inversin that is encoded in the genome of human.
Short Label hINVS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y283 (INVS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K41 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus   UniProt 23186163
S700 Phosphorylation PhosphoSitePlus
R726 Methylation PhosphoSitePlus
R734 Methylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
T795 Phosphorylation PhosphoSitePlus
R799 Methylation PhosphoSitePlus
T864 Phosphorylation PhosphoSitePlus   RLIMS-P 27220846
S865 Phosphorylation PhosphoSitePlus   RLIMS-P 27220846
T866 Phosphorylation PhosphoSitePlus   RLIMS-P 27220846
S980 Phosphorylation PhosphoSitePlus
K984 Acetylation PhosphoSitePlus
S985 Phosphorylation PhosphoSitePlus
K988 Acetylation PhosphoSitePlus
T990 O-Glycosylation GlyGen 35254053
S991 O-Glycosylation GlyGen 35254053
K1012 Ubiquitination PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
S1030 Phosphorylation PhosphoSitePlus
S1032 Phosphorylation PhosphoSitePlus
K1062 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K110 N110 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K110 R110 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S196 N196 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K310 I310 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R734 W734 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic, icgc ]
R799 K799 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1019 Y1019 Biomuta DOID:4159 / skin cancer [ cosmic ]