iPTMnet Report for Q9Y282 (ERGIC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y282 / ERGI3_HUMAN
Protein Name Endoplasmic reticulum-Golgi intermediate compartment protein 3
Gene Name Name: ERGIC3
Synonyms:C20orf47,ERV46,SDBCAG84;ORFNames:CGI-54,PRO0989;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y282
DAG View
PRO Name endoplasmic reticulum-Golgi intermediate compartment protein 3 (human)
Definition An endoplasmic reticulum-Golgi intermediate compartment protein 3 that is encoded in the genome of human.
Short Label hERGIC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y282 (ERGIC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 25944712
K6 Ubiquitination PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
C81 Methylation IEDB 31844290
Y83 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S116 O-Glycosylation GlyGen 25813380
S116 Phosphorylation PhosphoSitePlus   UniProt 23186163
S117 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
T130 O-Glycosylation GlyGen 30459171
S136 O-Glycosylation GlyGen 22661428
S136 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K190 Sumoylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
N241 N-Glycosylation GlyGen   UniProt 19159218
K289 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K15 N15 Biomuta DOID:9256 / colorectal cancer [ icgc ]
C81 R81 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S116 N116 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S136 F136 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
Y202 H202 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]