iPTMnet Report for Q9Y277 (VDAC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y277 / VDAC3_HUMAN
Protein Name Voltage-dependent anion-selective channel protein 3
Gene Name Name: VDAC3
Organism Homo sapiens (Human)

PRO ID PR:Q9Y277
DAG View
PRO Name voltage-dependent anion-selective channel protein 3 (human)
Definition A voltage-dependent anion-selective channel protein 3 that is encoded in the genome of human.
Short Label hVDAC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y277 (VDAC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
C2 Acetylation UniProt 19413330, 25944712
T4 Phosphorylation PhosphoSitePlus   UniProt 23186163
T6 Phosphorylation PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
K12 Acetylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
K15 Acetylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K20 Acetylation PhosphoSitePlus   UniProt 19608861
K20 Ubiquitination PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
K28 Acetylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
C36 S-Nitrosylation dbSNO 26338901
S44 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus   UniProt 25621951
K61 Acetylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus   UniProt 25621951
K63 Acetylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
C65 S-Nitrosylation dbSNO 20140087
Y67 Phosphorylation PhosphoSitePlus
T70 O-Glycosylation GlyGen 23301498, 27655845, 34725712, ...35132862, 35083852, 32870666, 34931806, 32119511
T70 Phosphorylation PhosphoSitePlus
K90 Acetylation PhosphoSitePlus   UniProt 19608861
K90 Ubiquitination PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
K109 Acetylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus   UniProt 25621951
K110 Acetylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus   UniProt 25621951
K113 Acetylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K119 Acetylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus   UniProt 25621951
Y173 Phosphorylation PhosphoSitePlus
K174 Acetylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K224 Acetylation PhosphoSitePlus
C229 Methylation IEDB 31844290
Y247 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
K266 Acetylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus   UniProt 25621951
K274 Ubiquitination PhosphoSitePlus   UniProt 25621951
Site PTM Type PTM Enzyme Score Source PMID
Y195 Phosphorylation HPRD 15592455
Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049654 (hVDAC3/InitMet-/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S44 F44 Biomuta DOID:1324 / lung cancer [ cosmic ]
T44 I44 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S45 F45 Biomuta DOID:1324 / lung cancer [ cosmic ]
T70 S70 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K109 N109 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K110 N110 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K224 E224 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K224 Q224 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y247 H247 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K274 E274 Biomuta DOID:1324 / lung cancer [ cosmic ]