iPTMnet Report for Q9Y263 (PLAA)
Protein Information
UniProt AC / UniProt ID | Q9Y263 / PLAP_HUMAN |
Protein Name | Phospholipase A-2-activating protein |
Gene Name | Name: PLAA Synonyms:PLAP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y263 |
PRO Name | phospholipase A-2-activating protein (human) |
Definition | A phospholipase A-2-activating protein that is encoded in the genome of human. |
Short Label | hPLAA |
Category | organism-gene |
Q9Y263 (PLAA) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T2 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
T6 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163, 20068231 | ||
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
C193 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
C263 | Methylation | score1 | IEDB | 31844290 | ||
R303 | Methylation | score1 | PhosphoSitePlus | |||
K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
K376 | Ubiquitination | score1 | PhosphoSitePlus | |||
S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
K399 | Ubiquitination | score1 | PhosphoSitePlus | |||
K456 | Acetylation | score1 | PhosphoSitePlus | |||
K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S481 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
T495 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y523 | Phosphorylation | score1 | PhosphoSitePlus | |||
K529 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
K537 | Ubiquitination | score1 | PhosphoSitePlus | |||
K538 | Ubiquitination | score1 | PhosphoSitePlus | |||
K554 | Acetylation | score1 | PhosphoSitePlus | |||
K554 | Ubiquitination | score1 | PhosphoSitePlus | |||
K556 | Ubiquitination | score1 | PhosphoSitePlus | |||
K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
K590 | Ubiquitination | score1 | PhosphoSitePlus | |||
K622 | Ubiquitination | score1 | PhosphoSitePlus | |||
C631 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K634 | Ubiquitination | score1 | PhosphoSitePlus | |||
K650 | Ubiquitination | score1 | PhosphoSitePlus | |||
K652 | Ubiquitination | score1 | PhosphoSitePlus | |||
S678 | Phosphorylation | score1 | PhosphoSitePlus | |||
K691 | Acetylation | score1 | PhosphoSitePlus | |||
K691 | Ubiquitination | score1 | PhosphoSitePlus | |||
K773 | Ubiquitination | score1 | PhosphoSitePlus | |||
K774 | Ubiquitination | score1 | PhosphoSitePlus | |||
K783 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K112 | T112 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K122 | N122 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S188 | L188 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
C263 | R263 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R303 | Q303 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
R303 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K393 | N393 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K538 | Q538 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K567 | Q567 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K774 | M774 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |