iPTMnet Report for Q9Y263 (PLAA)
Protein Information
| UniProt AC / UniProt ID | Q9Y263 / PLAP_HUMAN |
| Protein Name | Phospholipase A-2-activating protein |
| Gene Name | Name: PLAA Synonyms:PLAP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y263 |
| PRO Name | phospholipase A-2-activating protein (human) |
| Definition | A phospholipase A-2-activating protein that is encoded in the genome of human. |
| Short Label | hPLAA |
| Category | organism-gene |
Q9Y263 (PLAA) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S50 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163, 20068231 | ||
| K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C193 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C263 | Methylation | score1 | IEDB | 31844290 | ||
| R303 | Methylation | score1 | PhosphoSitePlus | |||
| K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K376 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K399 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K456 | Acetylation | score1 | PhosphoSitePlus | |||
| K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y477 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S481 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
| T495 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y523 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K529 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K537 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K538 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K554 | Acetylation | score1 | PhosphoSitePlus | |||
| K554 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K556 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K590 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K622 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C631 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| K634 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K650 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K652 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S678 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K691 | Acetylation | score1 | PhosphoSitePlus | |||
| K691 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K773 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K774 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K783 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K112 | T112 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K122 | N122 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S188 | L188 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| C263 | R263 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R303 | Q303 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| R303 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| K393 | N393 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K538 | Q538 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K567 | Q567 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| K774 | M774 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
DAG View