iPTMnet Report for Q9Y261 (FOXA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y261 / FOXA2_HUMAN
Protein Name Hepatocyte nuclear factor 3-beta
Gene Name Name: FOXA2
Synonyms:HNF3B,TCF3B;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y261
DAG View
PRO Name hepatocyte nuclear factor 3-beta (human)
Definition A hepatocyte nuclear factor 3-beta that is encoded in the genome of human.
Short Label hFOXA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y261 (FOXA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation PhosphoSitePlus
S107 Phosphorylation O15111 (CHUK) neXtProt   PhosphoSitePlus   Signor 22196886
S111 Phosphorylation O15111 (CHUK) neXtProt   PhosphoSitePlus   Signor 22196886
T156 Phosphorylation P31749 (AKT1) PhosphoSitePlus   RLIMS-P 14500912, 15949766
S212 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
Y248 Phosphorylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K259 Acetylation PhosphoSitePlus
K264 Acetylation PhosphoSitePlus
K274 Acetylation PhosphoSitePlus
K275 Acetylation PhosphoSitePlus
S283 Phosphorylation neXtProt 19478084
S295 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus   UniProt 24275569
S307 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus   UniProt 24275569


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S107 G107 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S212 F212 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y248 S248 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]