iPTMnet Report for Q9Y250 (LZTS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y250 / LZTS1_HUMAN
Protein Name Leucine zipper putative tumor suppressor 1
Gene Name Name: LZTS1
Synonyms:FEZ1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y250
DAG View
PRO Name leucine zipper putative tumor suppressor 1 (human)
Definition A leucine zipper putative tumor suppressor 1 that is encoded in the genome of human.
Short Label hLZTS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y250 (LZTS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
T433 Phosphorylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
Y550 Phosphorylation PhosphoSitePlus
Y554 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S21 L21 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S62 G62 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 F233 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S257 Y257 Biomuta DOID:1324 / lung cancer [ cosmic ]
S262 T262 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K362 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K362 E362 Biomuta DOID:3953 / adrenal gland cancer [ tcga ]