iPTMnet Report for Q9Y248 (GINS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y248 / PSF2_HUMAN
Protein Name DNA replication complex GINS protein PSF2
Gene Name Name: GINS2
Synonyms:PSF2;ORFNames:CGI-122,DC5,HSPC037;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y248
DAG View
PRO Name DNA replication complex GINS protein PSF2 (human)
Definition A DNA replication complex GINS protein PSF2 that is encoded in the genome of human.
Short Label hGINS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y248 (GINS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K70 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
S179 Phosphorylation HPRD   PhosphoSitePlus 18077418, 20068231
T180 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 18077418, 20068231
S182 Phosphorylation Q13535 (ATR) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17525332, 23186163, ...18077418, 21406692, 19651622, 18669648, 19690332, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 N73 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S182 P182 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S182 C182 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]