iPTMnet Report for Q9Y248 (GINS2)
Protein Information
UniProt AC / UniProt ID | Q9Y248 / PSF2_HUMAN |
Protein Name | DNA replication complex GINS protein PSF2 |
Gene Name | Name: GINS2 Synonyms:PSF2;ORFNames:CGI-122,DC5,HSPC037; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y248 |
PRO Name | DNA replication complex GINS protein PSF2 (human) |
Definition | A DNA replication complex GINS protein PSF2 that is encoded in the genome of human. |
Short Label | hGINS2 |
Category | organism-gene |
Q9Y248 (GINS2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
S179 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18077418, 20068231 | ||
T180 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17525332, 18077418, 20068231 | ||
S182 | Phosphorylation | Q13535 (ATR) | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 19413330, 17525332, 23186163, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K73 | N73 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S182 | P182 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S182 | C182 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |