Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y228 / T3JAM_HUMAN
Protein Name TRAF3-interacting JNK-activating modulator
Gene Name Name: TRAF3IP3
Synonyms:T3JAM;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y228
DAG View
PRO Name TRAF3-interacting JNK-activating modulator (human)
Definition A TRAF3-interacting JNK-activating modulator that is encoded in the genome of human.
Short Label hTRAF3IP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y228 (TRAF3IP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
T183 Phosphorylation PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 N3 Biomuta DOID:1909 / melanoma [ tcga ]
S110 Y110 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y185 * Biomuta DOID:3953 / adrenal gland cancer [ tcga ]
K202 I202 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S261 Y261 Biomuta DOID:3953 / adrenal gland cancer [ tcga ]
K406 T406 Biomuta DOID:363 / uterine cancer [ tcga ]
K480 R480 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]