iPTMnet Report for Q9Y217 (MTMR6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y217 / MTMR6_HUMAN
Protein Name Myotubularin-related protein 6
Gene Name Name: MTMR6
Organism Homo sapiens (Human)

PRO ID PR:Q9Y217
DAG View
PRO Name myotubularin-related protein 6 (human)
Definition A myotubularin-related protein 6 that is encoded in the genome of human.
Short Label hMTMR6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y217 (MTMR6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Ubiquitination PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
S21 Phosphorylation IEDB 32387766
C88 Methylation IEDB 31844290
K100 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K135 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
C156 Methylation IEDB 31844290
S170 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K226 Acetylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
S279 Phosphorylation IEDB 35494241
K283 Ubiquitination PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
C432 Methylation IEDB 31844290
K453 Ubiquitination PhosphoSitePlus
T454 O-Glycosylation GlyGen 29351928
S456 O-Glycosylation GlyGen 29351928
K466 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
Y468 Phosphorylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus   UniProt 24275569
S561 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
K565 Ubiquitination PhosphoSitePlus
T566 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
T574 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
S589 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y595 Phosphorylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
Y598 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y614 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S561 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S589 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K103 R103 Biomuta DOID:184 / bone cancer [ cosmic ]
Y108 C108 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C156 F156 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K226 I226 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T454 S454 Biomuta DOID:4159 / skin cancer [ cosmic ]
K466 T466 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K466 N466 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S556 A556 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K565 N565 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T566 N566 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S588 N588 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S588 R588 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]