iPTMnet Report for Q9Y210 (TRPC6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y210 / TRPC6_HUMAN
Protein Name Short transient receptor potential channel 6
Gene Name Name: TRPC6
Synonyms:TRP6;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y210
DAG View
PRO Name short transient receptor potential channel 6 (human)
Definition A short transient receptor potential channel 6 that is encoded in the genome of human.
Short Label hTRPC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y210 (TRPC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
R11 Methylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S14 O-Glycosylation GlyGen 36936781
S14 Phosphorylation PhosphoSitePlus   RLIMS-P 28877958
R16 Methylation PhosphoSitePlus
S28 Phosphorylation RLIMS-P 22001259
Y31 Phosphorylation PhosphoSitePlus
T70 O-Glycosylation GlyGen 36936781
T70 Phosphorylation Q13976 (PRKG1) phospho.ELM   PhosphoSitePlus   RLIMS-P 19961855, 17081983, 23814119
T221 O-Glycosylation GlyGen 36936781
S270 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
S322 Phosphorylation Q13976 (PRKG1) PhosphoSitePlus   RLIMS-P 19961855
T402 Phosphorylation IEDB 35494241
N473 N-Glycosylation GlyGen   UniProt 12970363, 29671580, 24190977
N561 N-Glycosylation GlyGen   UniProt 12970363
Y612 Phosphorylation PhosphoSitePlus
T759 Phosphorylation PhosphoSitePlus
Y775 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S815 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087
S836 Phosphorylation PhosphoSitePlus
S839 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
S892 Phosphorylation PhosphoSitePlus
Y896 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N473 N-Glycosylation PRO 29671580
S815 Phosphorylation HPRD 18088087
S839 Phosphorylation HPRD 18088087


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R16 W16 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T221 S221 Biomuta DOID:4159 / skin cancer [ cosmic ]
S270 Y270 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S272 Y272 Biomuta DOID:1324 / lung cancer [ cosmic ]
S282 I282 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S322 L322 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T402 K402 Biomuta DOID:3571 / liver cancer [ cosmic ]
N473 D473 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y775 C775 Biomuta DOID:3571 / liver cancer [ cosmic ]
S836 I836 Biomuta DOID:363 / uterine cancer [ icgc ]