iPTMnet Report for Q9WVH4 (Foxo3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9WVH4 / FOXO3_MOUSE
Protein Name Forkhead box protein O3
Gene Name Name: Foxo3
Synonyms:Fkhr2;
Organism Mus musculus (Mouse)

PRO ID PR:Q9WVH4
DAG View
PRO Name forkhead box protein O3 (mouse)
Definition A forkhead box protein O3 that is encoded in the genome of mouse.
Short Label mFOXO3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9WVH4 (Foxo3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
T32 Phosphorylation PhosphoSitePlus   RLIMS-P 26694365, 22586590, 33510167, ...10102273, 32850784, 23964069, 20332342
T32 Phosphorylation P31750 (Akt1) PhosphoSitePlus 10102273
S43 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
K241 Acetylation PhosphoSitePlus   UniProt 23806337
S252 Phosphorylation PhosphoSitePlus
S256 Phosphorylation RLIMS-P 24174672
K258 Acetylation PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
K270 Methylation IntAct 22402663
S279 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus   UniProt 21183079
S298 Phosphorylation PhosphoSitePlus   UniProt 23805378
S299 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus
K568 Acetylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P31750 (Akt1) S473 Q9WVH4 (Foxo3) decreased_association eFIP 24067903