iPTMnet Report Q9WTK7 Stk11

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9WTK7 / STK11_MOUSE
Protein Name	Serine/threonine-protein kinase STK11 precursor
Gene Name	Name: Stk11 Synonyms:Lkb1;
Organism	Mus musculus (Mouse)

PRO ID	PR:Q9WTK7 DAG View
PRO Name	serine/threonine-protein kinase STK11 (mouse)
Definition	A serine/threonine-protein kinase STK11 that is encoded in the genome of mouse.
Short Label	mSTK11
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9WTK7 (Stk11) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S31	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P UniProt	11853558, 21183079, 32841502, ...17114649
	T32	Phosphorylation		score1	PhosphoSitePlus
	Y36	Phosphorylation		score1	PhosphoSitePlus
	Y60	Phosphorylation		score1	PhosphoSitePlus
	Y156	Phosphorylation		score1	PhosphoSitePlus
	Y166	Phosphorylation		score1	PhosphoSitePlus
	Y261	Phosphorylation		score4	PhosphoSitePlus RLIMS-P	24586906, 20142099
	S325	Phosphorylation		score3	phospho.ELM PhosphoSitePlus UniProt	11853558
	S334	Phosphorylation		score0	RLIMS-P	22611470
	T336	Phosphorylation	Q9QZY4 (Lkb1) , Q9WTK7 (Stk11)	score3	phospho.ELM PhosphoSitePlus UniProt	11853558
	Y365	Phosphorylation		score4	PhosphoSitePlus RLIMS-P	24586906, 20142099
	T366	Phosphorylation	Q9QZY4 (Lkb1) , Q62388 (Atm) , P97313 (Prkdc) , Q9WTK7 (Stk11)	score4	phospho.ELM PhosphoSitePlus UniProt	20864035, 25329316, 11853558, ...12234250
	S424	Phosphorylation		score1	PhosphoSitePlus
	S431	Phosphorylation	Q9WTK7 (Stk11) , Q62388 (Atm) , P18653 (Rps6ka1) , P97313 (Prkdc) , P05132 (Prkaca) , Q8BSK8 (Rps6kb1) , Q8C050 (Rps6ka5)	score4	phospho.ELM PhosphoSitePlus RLIMS-P UniProt	12234250, 17482548, 10642527, ...27849007, 16407220, 24295069, 17482549, 11297520

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y36	Phosphorylation	PR:P06240 (mLCK)	score2	PRO	21487392
	Y261	Phosphorylation	PR:P39688 (mFYN) , PR:P06240 (mLCK)	score3	PRO	18854309, 21487392, 20142099
	Y365	Phosphorylation	PR:P06240 (mLCK) , PR:P39688 (mFYN)	score3	PRO	18854309, 21487392, 20142099
	S431	Phosphorylation		score2	PRO	24295069

Q9WTK7 (Stk11) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	O88643 (Pak1)	T109	score2	PhosphoSitePlus	20400510
	Q5EG47 (Prkaa1)	T183	score2	PhosphoSitePlus	14985505
	Q60670 (Sik1)	T182	score2	RLIMS-P+	18946175
	Q9WTK7 (Stk11)	T336	score3	PhosphoSitePlus UniProt	11853558
	Q9WTK7 (Stk11)	T366	score3	PhosphoSitePlus UniProt	11853558
	Q9WTK7 (Stk11)	S431	score2	UniProt	10642527

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000036893 (mSTK11/iso:1/Phos:1)	pY261,pY365	PR:P39688 (mFYN)	PRO	18854309, 20142099
	PR:000036995 (mSTK11/iso:1/Phos:2)	pY36,pY261,pY365	PR:P06240 (mLCK)	PRO	21487392
	PR:000045395 (mSTK11/iso:1/FarnPhos:1)	pS431		PRO	24295069