Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQF2 / JIP1_HUMAN
Protein Name C-Jun-amino-terminal kinase-interacting protein 1
Gene Name Name: MAPK8IP1
Synonyms:IB1,JIP1,PRKM8IP;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQF2
DAG View
PRO Name C-Jun-amino-terminal kinase-interacting protein 1 (human)
Definition A C-Jun-amino-terminal kinase-interacting protein 1 that is encoded in the genome of human.
Short Label hMAPK8IP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQF2 (MAPK8IP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation P45983 (MAPK8) HPRD   phospho.ELM   PhosphoSitePlus 12756254
S29 Phosphorylation P45983 (MAPK8) HPRD   phospho.ELM   PhosphoSitePlus 12756254
S40 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
R86 Methylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
T103 Phosphorylation P45984 (MAPK9) , P45983 (MAPK8) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12756254, 15998799, 15911620
K128 Acetylation PhosphoSitePlus
S152 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
S181 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S187 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S193 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S195 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S196 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S197 Phosphorylation P45983 (MAPK8) HPRD   phospho.ELM   PhosphoSitePlus 12756254
T201 Phosphorylation PhosphoSitePlus
T205 Phosphorylation P45983 (MAPK8) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 12756254
S214 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S235 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16195223
S240 Phosphorylation PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus
T284 Phosphorylation P45983 (MAPK8) HPRD   phospho.ELM   PhosphoSitePlus 12756254
S311 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S328 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S330 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S340 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S341 Phosphorylation P45983 (MAPK8) HPRD   phospho.ELM   PhosphoSitePlus 12756254
S355 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S366 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
S369 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S407 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S409 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
T411 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S421 Phosphorylation P45983 (MAPK8) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 23897889, 12756254
S444 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S447 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
T448 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16195223
S469 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
S471 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
S472 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
S473 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16195223
S574 Phosphorylation PhosphoSitePlus
T702 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9UQF2 (MAPK8IP1) S421 P33176 (KIF5B) unknown eFIP 23897889
Phosphorylation Q9UQF2 (MAPK8IP1) T103 P31749 (AKT1) unknown eFIP 15998799


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S181 Y181 Biomuta DOID:363 / uterine cancer [ tcga ]
S311 F311 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:1909 / melanoma [ tcga ] DOID:1324 / lung cancer [ tcga ]
S421 L421 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S444 F444 Biomuta DOID:1909 / melanoma [ tcga ]