Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQD0 / SCN8A_HUMAN
Protein Name Sodium channel protein type 8 subunit alpha
Gene Name Name: SCN8A
Synonyms:MED;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQD0
DAG View
PRO Name sodium channel protein type 8 subunit alpha (human)
Definition A sodium channel protein type 8 subunit alpha that is encoded in the genome of human.
Short Label hSCN8A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQD0 (SCN8A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
K509 Methylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S553 Phosphorylation Q16539 (MAPK14) neXtProt 16014723
S561 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
T642 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S690 Phosphorylation PhosphoSitePlus
K1487 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S553 L553 Biomuta DOID:1909 / melanoma [ cosmic ] DOID:11934 / head and neck cancer [ tcga ]