iPTMnet Report for Q9UQC9 (CLCA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQC9 / CLCA2_HUMAN
Protein Name Calcium-activated chloride channel regulator 2 precursor
Gene Name Name: CLCA2
Synonyms:CACC3;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQC9
DAG View
PRO Name calcium-activated chloride channel regulator 2 (human)
Definition A calcium-activated chloride channel regulator 2 that is encoded in the genome of human.
Short Label hCLCA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQC9 (CLCA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N74 N-Glycosylation GlyGen 29741879
T76 Phosphorylation PhosphoSitePlus
N150 N-Glycosylation GlyGen 23090970, 24190977
Y155 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
T388 Phosphorylation PhosphoSitePlus
N556 N-Glycosylation GlyGen 23090970, 24190977
N580 N-Glycosylation GlyGen 23090970, 24190977
N637 N-Glycosylation GlyGen 29741879
K667 Acetylation PhosphoSitePlus
N822 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S873 Phosphorylation PhosphoSitePlus
S876 O-Glycosylation GlyGen 29351928
S876 Phosphorylation PhosphoSitePlus
S879 O-Glycosylation GlyGen 29351928
K935 Acetylation PhosphoSitePlus
K936 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S157 L157 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T388 A388 Biomuta DOID:263 / kidney cancer [ cosmic ]
N556 S556 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
K667 Q667 Biomuta DOID:263 / kidney cancer [ cosmic ]
S873 F873 Biomuta DOID:4159 / skin cancer [ cosmic ]
S879 F879 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K935 N935 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K936 R936 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]