iPTMnet Report for Q9UQC2 (GAB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQC2 / GAB2_HUMAN
Protein Name GRB2-associated-binding protein 2
Gene Name Name: GAB2
Synonyms:KIAA0571;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQC2
DAG View
PRO Name GRB2-associated-binding protein 2 (human)
Definition A GRB2-associated-binding protein 2 that is encoded in the genome of human.
Short Label hGAB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQC2 (GAB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S2 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23607741, 23186163
Y48 Phosphorylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus   UniProt 19172738
S140 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19172738, 18220336
S141 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 27025927, 19172738
S146 Phosphorylation RLIMS-P 27025927
S147 Phosphorylation RLIMS-P 27025927
S148 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19172738
S149 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23607741, 23186163, 19172738
S159 Phosphorylation P31749 (AKT1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 11782427, 23607741, 23045700, ...27324437, 19172738
S164 Phosphorylation PhosphoSitePlus   UniProt 19172738
T171 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23607741, 27025927, 30755611, ...19172738
S212 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus   UniProt 19172738
S223 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19172738
Y249 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19172738
T265 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107, 12522270
T278 Phosphorylation PhosphoSitePlus   UniProt 19172738
S281 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23607741, 19172738
S285 Phosphorylation PhosphoSitePlus   UniProt 23186163
T287 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 27025927, 23186163, 19172738
Y293 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11334882, 19172738
T294 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus   RLIMS-P 27025927
S322 Phosphorylation PhosphoSitePlus
Y324 Phosphorylation phospho.ELM   PhosphoSitePlus 16497976
T331 Phosphorylation PhosphoSitePlus   UniProt 19172738
S368 Phosphorylation PhosphoSitePlus   UniProt 23186163
T385 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 27025927, 19172738
T391 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23607741, 23186163, 19172738, ...27025927
S404 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 30755611, 19172738
T408 Phosphorylation PhosphoSitePlus
Y409 Phosphorylation PhosphoSitePlus
Y411 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus   UniProt 23186163
S425 Phosphorylation PhosphoSitePlus   UniProt 23186163
S427 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
Y452 Phosphorylation P08631 (HCK) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 22858987, 23607741, 31756944, ...30755611, 17513616, 24349524, 11334882
S459 Phosphorylation PhosphoSitePlus   RLIMS-P 27025927
S472 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
Y476 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 27025927, 11334882, 30755611
S480 Phosphorylation PhosphoSitePlus   UniProt 19172738
S488 Phosphorylation PhosphoSitePlus
Y491 Phosphorylation PhosphoSitePlus   RLIMS-P 23607741
K542 Methylation PhosphoSitePlus
S543 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19172738
T546 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
Y563 Phosphorylation PhosphoSitePlus
Y584 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 11334882, 30755611
S611 Phosphorylation PhosphoSitePlus
Y614 Phosphorylation P43403 (ZAP70) IntAct   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor 15356145, 11572860, 15170389
S622 Phosphorylation PhosphoSitePlus   UniProt 19172738
S623 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15356145, 19172738, 30755611
S625 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
T632 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
S634 Phosphorylation RLIMS-P 23607741
T636 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
Y643 Phosphorylation O60674 (JAK2) IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 27025927, 18644434, ...15170389, 15356145, 28122968
T651 Phosphorylation PhosphoSitePlus
T657 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S140 Phosphorylation HPRD 19651622
S148 Phosphorylation HPRD 19651622
S159 Phosphorylation P31749 (AKT1) HPRD 11782427
Y266 Phosphorylation HPRD 12522270
Y324 Phosphorylation HPRD 16497976
T385 Phosphorylation HPRD 19007248
S404 Phosphorylation HPRD 19413330
S543 Phosphorylation HPRD 18669648
Y614 Phosphorylation P43403 (ZAP70) HPRD 11572860
S623 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) HPRD 15356145
Y643 Phosphorylation HPRD 19651622


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047486 (hGAB2/Phos:2) pY452,pY476,pY584 PRO
PR:000047487 (hGAB2/Phos:3) pY452,pY476,pY584,pY614,pY643 PRO
PR:000047488 (hGAB2/PhosTyr+) p PRO