Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQB9 / AURKC_HUMAN
Protein Name Aurora kinase C
Gene Name Name: AURKC
Synonyms:AIE2,AIK3,AIRK3,ARK3,STK13;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQB9
DAG View
PRO Name aurora kinase C (human)
Definition An aurora kinase C that is encoded in the genome of human.
Short Label hAURKC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQB9 (AURKC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation PhosphoSitePlus
T39 Phosphorylation RLIMS-P 31320618
K53 Ubiquitination PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
T198 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P 31320618, 18220336, 18669648, ...11879579
T202 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
Y205 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T198 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T164 Phosphorylation HPRD   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
T179 Phosphorylation HPRD 18669648


Q9UQB9 (AURKC) as PTM Enzyme



Substrate Site Score Source PMID
O75410 (TACC1) S228 neXtProt   PhosphoSitePlus 21531210
P68431 (H3C12) S11 Signor 12588998, 14583461


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T39 I39 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S77 L77 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K197 T197 Biomuta DOID:5041 / esophageal cancer [ icgc ]
T198 A198 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]