iPTMnet Report for Q9UQB3 (CTNND2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQB3 / CTND2_HUMAN
Protein Name Catenin delta-2
Gene Name Name: CTNND2
Synonyms:NPRAP;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQB3
DAG View
PRO Name catenin delta-2 (human)
Definition A catenin delta-2 that is encoded in the genome of human.
Short Label hCTNND2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQB3 (CTNND2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
S303 Phosphorylation neXtProt   PhosphoSitePlus 20573893
S305 Phosphorylation PhosphoSitePlus
S310 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S315 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S322 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S323 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S327 O-Glycosylation GlyGen 30379171, 35132862, 28657654
Y372 Phosphorylation PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
Y399 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
S456 O-Glycosylation GlyGen 30379171, 35132862, 28657654
T457 Phosphorylation neXtProt   PhosphoSitePlus 17993462
T457 Phosphorylation P31749 (AKT1) neXtProt 17993462
S461 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S461 Phosphorylation PhosphoSitePlus
S474 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S490 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
Y499 Phosphorylation PhosphoSitePlus
Y503 Phosphorylation PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
Y516 Phosphorylation PhosphoSitePlus
S517 O-Glycosylation GlyGen 30379171, 35132862, 28657654
S517 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K926 Ubiquitination PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
Y932 Phosphorylation PhosphoSitePlus
S1002 Phosphorylation PhosphoSitePlus
T1042 Phosphorylation PhosphoSitePlus
T1056 Phosphorylation neXtProt 19706605
T1056 Phosphorylation P49841 (GSK3B) neXtProt 19706605
S1060 Phosphorylation PhosphoSitePlus
S1065 Phosphorylation PhosphoSitePlus
S1070 O-Glycosylation GlyGen 30379171
S1072 O-Glycosylation GlyGen 30379171
S1072 Phosphorylation PhosphoSitePlus
Y1090 Phosphorylation PhosphoSitePlus
Y1099 Phosphorylation PhosphoSitePlus
T1122 Phosphorylation PhosphoSitePlus
S1127 Phosphorylation PhosphoSitePlus
Y1154 Phosphorylation PhosphoSitePlus
Y1157 Phosphorylation PhosphoSitePlus
S1193 Phosphorylation PhosphoSitePlus
Y1197 Phosphorylation PhosphoSitePlus
Y1201 Phosphorylation PhosphoSitePlus
Y1207 Phosphorylation PhosphoSitePlus
Y1217 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation HPRD 15345747
S474 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 N32 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S201 N201 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S322 Y322 Biomuta DOID:4159 / skin cancer [ cosmic ]
S322 P322 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S323 L323 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y372 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y399 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y424 C424 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S456 I456 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S456 R456 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T457 R457 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y516 * Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S517 R517 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S517 I517 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S537 I537 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K926 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K926 T926 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1002 Y1002 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1042 A1042 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1056 K1056 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1056 M1056 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1060 F1060 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1072 N1072 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1127 F1127 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1193 F1193 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1207 * Biomuta DOID:1324 / lung cancer [ cosmic ]