iPTMnet Report for Q9UQ13 (SHOC2)
Protein Information
| UniProt AC / UniProt ID | Q9UQ13 / SHOC2_HUMAN |
| Protein Name | Leucine-rich repeat protein SHOC-2 |
| Gene Name | Name: SHOC2 Synonyms:KIAA0862; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UQ13 |
| PRO Name | leucine-rich repeat protein SHOC-2 (human) |
| Definition | A leucine-rich repeat protein SHOC-2 that is encoded in the genome of human. |
| Short Label | hSHOC2 |
| Category | organism-gene |
DAG ViewQ9UQ13 (SHOC2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T71 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29383184 | ||
| S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C144 | Methylation | score1 | IEDB | 31844290 | ||
| K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C260 | Methylation | score1 | IEDB | 31844290 | ||
| S297 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29383184 | ||
| S307 | Phosphorylation | score1 | IEDB | 30784271 | ||
| C342 | Methylation | score1 | IEDB | 31844290 | ||
| K369 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K383 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K439 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K459 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K471 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K475 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T507 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S566 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y578 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T71 | M71 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S102 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S117 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K212 | T212 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S307 | N307 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K459 | T459 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T507 | S507 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] |
