iPTMnet Report for Q9UPW8 (UNC13A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPW8 / UN13A_HUMAN
Protein Name Protein unc-13 homolog A
Gene Name Name: UNC13A
Synonyms:KIAA1032;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPW8
DAG View
PRO Name protein unc-13 homolog A (human)
Definition A protein unc-13 homolog A that is encoded in the genome of human.
Short Label hUNC13A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPW8 (UNC13A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S222 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
Y700 Phosphorylation PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
Y869 Phosphorylation PhosphoSitePlus
Y888 Phosphorylation PhosphoSitePlus
S988 Phosphorylation PhosphoSitePlus
S1245 Phosphorylation PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
K1581 Acetylation PhosphoSitePlus
K1582 Acetylation PhosphoSitePlus
T1587 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S256 R256 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S443 P443 Biomuta DOID:1324 / lung cancer [ cosmic ]
S504 R504 Biomuta DOID:1324 / lung cancer [ cosmic ]
S696 F696 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S734 F734 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
Y869 H869 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1581 M1581 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1582 E1582 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]