iPTMnet Report for Q9UPU9 (SAMD4A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPU9 / SMAG1_HUMAN
Protein Name Protein Smaug homolog 1
Gene Name Name: SAMD4A
Synonyms:KIAA1053,SAMD4,SMAUG1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPU9
DAG View
PRO Name protein Smaug homolog 1 (human)
Definition A protein Smaug homolog 1 that is encoded in the genome of human.
Short Label hSAMD4A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPU9 (SAMD4A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y128 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y171 Phosphorylation PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
Y418 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus   UniProt 18669648
S422 Phosphorylation PhosphoSitePlus
T423 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus   UniProt 18669648
S447 Phosphorylation PhosphoSitePlus
Y567 Phosphorylation PhosphoSitePlus
R573 Methylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
T583 Phosphorylation PhosphoSitePlus
Y599 Phosphorylation PhosphoSitePlus
R604 Methylation PhosphoSitePlus
T630 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
T663 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
T717 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S254 P254 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S254 F254 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S254 Y254 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T424 S424 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T424 P424 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y567 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T583 M583 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ]
R604 Q604 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R604 W604 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S671 F671 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S716 F716 Biomuta [ cosmic ]
T717 A717 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]