iPTMnet Report for Q9UPU7 (TBC1D2B)
Protein Information
| UniProt AC / UniProt ID | Q9UPU7 / TBD2B_HUMAN |
| Protein Name | TBC1 domain family member 2B |
| Gene Name | Name: TBC1D2B Synonyms:KIAA1055; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UPU7 |
| PRO Name | TBC1 domain family member 2B (human) |
| Definition | A TBC1 domain family member 2B that is encoded in the genome of human. |
| Short Label | hTBC1D2B |
| Category | organism-gene |
Q9UPU7 (TBC1D2B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R54 | Methylation | score1 | PhosphoSitePlus | |||
| R56 | Methylation | score1 | PhosphoSitePlus | |||
| K120 | Acetylation | score1 | PhosphoSitePlus | |||
| K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S155 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K163 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S316 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S317 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K355 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K392 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K401 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S431 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S473 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K497 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K505 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K527 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K534 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S540 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y542 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T551 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C554 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| T561 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S577 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y594 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y597 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K610 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K614 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K621 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K698 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K702 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K708 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K722 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y787 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y788 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T789 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T791 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K809 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K886 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T948 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S949 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S957 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 18318008, 18669648, ... | ||
| T963 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R56 | C56 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K137 | N137 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K221 | E221 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S230 | L230 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
| S316 | N316 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S317 | N317 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S328 | N328 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K355 | N355 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S473 | F473 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K501 | T501 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K501 | E501 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] | |
| S577 | G577 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T791 | N791 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
DAG View