iPTMnet Report for Q9UPU3 (SORCS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPU3 / SORC3_HUMAN
Protein Name VPS10 domain-containing receptor SorCS3 precursor
Gene Name Name: SORCS3
Synonyms:KIAA1059;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPU3
DAG View
PRO Name VPS10 domain-containing receptor SorCS3 (human)
Definition A VPS10 domain-containing receptor SorCS3 that is encoded in the genome of human.
Short Label hSORCS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPU3 (SORCS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T148 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
T239 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
K1023 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S176 L176 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T239 I239 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S322 A322 Biomuta DOID:2531 / hematologic cancer [ cosmic ]