Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPT8 / ZC3H4_HUMAN
Protein Name Zinc finger CCCH domain-containing protein 4
Gene Name Name: ZC3H4
Synonyms:C19orf7,KIAA1064;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPT8
DAG View
PRO Name zinc finger CCCH domain-containing protein 4 (human)
Definition A zinc finger CCCH domain-containing protein 4 that is encoded in the genome of human.
Short Label hZC3H4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPT8 (ZC3H4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
T72 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17525332
T75 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S92 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 17081983, 20068231
S94 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 17081983, 20068231
S131 Phosphorylation HPRD   PhosphoSitePlus 18452278
S132 Phosphorylation HPRD   PhosphoSitePlus 18452278
S133 Phosphorylation HPRD   PhosphoSitePlus 18452278
S137 Phosphorylation HPRD   PhosphoSitePlus 18452278
S143 Phosphorylation HPRD   PhosphoSitePlus 18452278
S146 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y155 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y158 Phosphorylation PhosphoSitePlus 18698806
Y158 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
S159 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y162 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
Y204 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus 18698806
Y247 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
R270 Methylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
T454 Phosphorylation HPRD   PhosphoSitePlus 18452278
S566 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
T802 Phosphorylation PhosphoSitePlus
Y806 Phosphorylation PhosphoSitePlus
S807 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 24275569, ...19690332, 20068231
S808 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 19690332, ...20068231
S815 Phosphorylation PhosphoSitePlus
S816 Phosphorylation PhosphoSitePlus
S835 O-Glycosylation GlyGen 29237092, 29351928
T898 Phosphorylation HPRD   PhosphoSitePlus 20068231
S899 O-Glycosylation GlyGen 29237092, 29351928
S899 Phosphorylation PhosphoSitePlus
K900 Acetylation PhosphoSitePlus
S904 O-Glycosylation GlyGen 29237092, 29351928
S904 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S907 O-Glycosylation GlyGen 29237092, 29351928
S907 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 18669648, 24275569, ...20068231
S908 O-Glycosylation GlyGen 29237092, 29351928
S908 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 20068231, ...18452278
S914 Phosphorylation HPRD   PhosphoSitePlus 18452278
T967 Phosphorylation PhosphoSitePlus
K970 Acetylation PhosphoSitePlus
T1056 Phosphorylation PhosphoSitePlus
S1059 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation PhosphoSitePlus
S1104 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 18452278, ...18669648, 20166139, 19690332, 20068231
T1106 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20166139, 18669648, 18452278
S1108 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1110 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1114 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 19664995, ...18452278, 19651622, 18669648, 24275569, 19690332, 20068231
T1118 Phosphorylation PhosphoSitePlus
Y1121 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T1153 Phosphorylation PhosphoSitePlus
T1161 Phosphorylation PhosphoSitePlus
T1167 Phosphorylation PhosphoSitePlus
T1201 Phosphorylation PhosphoSitePlus
T1210 Phosphorylation PhosphoSitePlus
Y1218 Phosphorylation PhosphoSitePlus 18698806
Y1218 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
T1235 Phosphorylation PhosphoSitePlus
T1265 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S1267 Phosphorylation HPRD   PhosphoSitePlus 17081983, 19664995
S1269 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 16964243, ...15302935, 19664995, 19651622, 18669648, 19690332, 20068231
S1275 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...16964243, 18220336, 18767875, 15302935, 19664995, 18452278, 19651622, 19664994, 18669648, 24275569, 20068231
S1286 Phosphorylation PhosphoSitePlus
K1288 Ubiquitination PhosphoSitePlus
T1297 Phosphorylation HPRD 20068231
S1299 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T7 N7 Biomuta DOID:1324 / lung cancer [ cosmic ]
S137 C137 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T175 M175 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K222 R222 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y364 C364 Biomuta DOID:263 / kidney cancer [ cosmic ]
S835 L835 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S907 A907 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S1059 L1059 Biomuta DOID:10534 / stomach cancer [ icgc ]
S1104 T1104 Biomuta DOID:0070003 / blastoma [ cosmic ]
T1201 I1201 Biomuta DOID:10534 / stomach cancer [ tcga ]
T1210 I1210 Biomuta DOID:1909 / melanoma [ tcga ]
T1265 M1265 Biomuta DOID:363 / uterine cancer [ tcga ]
S1267 * Biomuta DOID:1909 / melanoma [ cosmic ]
T1297 M1297 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]