iPTMnet Report for Q9UPT5 (EXOC7)
Protein Information
| UniProt AC / UniProt ID | Q9UPT5 / EXOC7_HUMAN |
| Protein Name | Exocyst complex component 7 |
| Gene Name | Name: EXOC7 Synonyms:EXO70,KIAA1067; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UPT5 |
| PRO Name | exocyst complex component 7 (human) |
| Definition | An exocyst complex component 7 that is encoded in the genome of human. |
| Short Label | hEXOC7 |
| Category | organism-gene |
Q9UPT5 (EXOC7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S47 | Phosphorylation | score0 | RLIMS-P | 31913283 | ||
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S59 | Phosphorylation | score0 | RLIMS-P | 31913283 | ||
| K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C83 | Methylation | score1 | IEDB | 31844290 | ||
| S89 | Phosphorylation | score0 | RLIMS-P | 31913283 | ||
| Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K138 | Acetylation | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K140 | Acetylation | score1 | PhosphoSitePlus | |||
| K147 | Acetylation | score1 | PhosphoSitePlus | |||
| K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S194 | Phosphorylation | score0 | RLIMS-P | 31913283 | ||
| S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | P28482 (MAPK1) , P27361 (MAPK3) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor | 22595671, 30917119, 31913283, ... | |
| T271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C367 | Methylation | score1 | IEDB | 31844290 | ||
| K443 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T466 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K484 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C550 | Methylation | score1 | IEDB | 31844290 | ||
| K563 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K633 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K653 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K657 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K668 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K671 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K702 | Acetylation | score1 | PhosphoSitePlus | |||
| K714 | Acetylation | score1 | PhosphoSitePlus | |||
| K717 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K19 | R19 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| K55 | T55 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| C83 | Y83 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S225 | R225 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S230 | P230 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S243 | Y243 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K291 | R291 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K633 | N633 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View