iPTMnet Report for Q9UPQ9 (TNRC6B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPQ9 / TNR6B_HUMAN
Protein Name Trinucleotide repeat-containing gene 6B protein
Gene Name Name: TNRC6B
Synonyms:KIAA1093;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPQ9
DAG View
PRO Name trinucleotide repeat-containing gene 6B protein (human)
Definition A trinucleotide repeat-containing gene 6B protein that is encoded in the genome of human.
Short Label hTNRC6B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPQ9 (TNRC6B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T43 O-Glycosylation GlyGen   IEDB 26280087
S61 Phosphorylation PhosphoSitePlus
R85 Methylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
T327 O-Glycosylation GlyGen 30379171, 34019948, 30397120, ...35132862, 35254053
T327 Phosphorylation PhosphoSitePlus
S343 O-Glycosylation GlyGen 30397120, 30379171, 34019948, ...35254053, 35132862, 30620550
S384 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
C557 Methylation IEDB 31844290
S563 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus
T574 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
T650 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
T658 Phosphorylation PhosphoSitePlus
T660 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
S879 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 24275569
S914 Phosphorylation PhosphoSitePlus
S992 Phosphorylation PhosphoSitePlus
S1011 Phosphorylation PhosphoSitePlus
K1051 Methylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
Y1134 Phosphorylation PhosphoSitePlus
R1209 Methylation PhosphoSitePlus
T1213 Phosphorylation PhosphoSitePlus
R1225 Methylation PhosphoSitePlus
S1302 Phosphorylation PhosphoSitePlus
R1306 Methylation PhosphoSitePlus
R1315 Methylation PhosphoSitePlus
S1336 Phosphorylation PhosphoSitePlus
K1344 Ubiquitination PhosphoSitePlus
Y1382 Phosphorylation PhosphoSitePlus
T1392 Phosphorylation PhosphoSitePlus
S1394 Phosphorylation PhosphoSitePlus
R1429 Methylation PhosphoSitePlus
S1432 Phosphorylation PhosphoSitePlus
Y1434 Phosphorylation PhosphoSitePlus
S1461 Phosphorylation PhosphoSitePlus
T1464 Phosphorylation PhosphoSitePlus
Y1499 Phosphorylation PhosphoSitePlus
T1509 Phosphorylation PhosphoSitePlus
T1511 Phosphorylation PhosphoSitePlus
S1536 O-Glycosylation GlyGen 30379171, 34019948, 30397120, ...35132862, 35254053
S1539 Phosphorylation PhosphoSitePlus
K1566 Ubiquitination PhosphoSitePlus
S1567 Phosphorylation PhosphoSitePlus
S1570 Phosphorylation PhosphoSitePlus
T1596 Phosphorylation PhosphoSitePlus
S1612 Phosphorylation PhosphoSitePlus
S1615 Phosphorylation PhosphoSitePlus
S1616 Phosphorylation PhosphoSitePlus
R1623 Methylation PhosphoSitePlus
R1631 Methylation PhosphoSitePlus
Y1648 Phosphorylation PhosphoSitePlus
S1816 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
S1830 Phosphorylation PhosphoSitePlus
S1832 Phosphorylation PhosphoSitePlus   UniProt 20068231
Site PTM Type PTM Enzyme Score Source PMID
S406 Phosphorylation HPRD 18691976
T407 Phosphorylation HPRD 18691976
S432 Phosphorylation HPRD 20068231
S443 Phosphorylation HPRD 20068231
S879 Phosphorylation HPRD 18767875, 19664994, 20068231, ...18452278
T927 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S937 Phosphorylation PhosphoSitePlus
Y1081 Phosphorylation PhosphoSitePlus
K1084 Ubiquitination PhosphoSitePlus
S1110 Phosphorylation HPRD 20068231
S1226 Phosphorylation HPRD 19651622, 20068231
S1322 Phosphorylation HPRD 18669648
Y1324 Phosphorylation HPRD 18669648
S1351 Phosphorylation HPRD 18669648
T1401 Phosphorylation HPRD 18669648, 20068231
S1426 Phosphorylation HPRD 18669648
S1429 Phosphorylation HPRD 18669648
S1460 Phosphorylation HPRD 20068231
S1706 Phosphorylation HPRD 17322306, 18669648, 19664995, ...20068231
S1720 Phosphorylation HPRD 18669648, 20068231
S1722 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
T29 Phosphorylation HPRD   PhosphoSitePlus 20068231
S36 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y387 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
S416 Phosphorylation HPRD 20068231
S532 Phosphorylation HPRD 19651622, 20068231
S628 Phosphorylation HPRD 18669648
Y630 Phosphorylation HPRD 18669648
S657 Phosphorylation HPRD 18669648
T707 Phosphorylation HPRD 18669648, 20068231
S732 Phosphorylation HPRD 18669648
S735 Phosphorylation HPRD 18669648
S766 Phosphorylation HPRD 20068231
S1012 Phosphorylation HPRD 17322306, 18669648, 19664995, ...20068231
S1026 Phosphorylation HPRD 18669648, 20068231
S1028 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 G13 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R85 S85 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S261 Y261 Biomuta DOID:363 / uterine cancer [ icgc ]
S424 Y424 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S504 P504 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S564 Y564 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T565 A565 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T574 S574 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S583 I583 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S914 F914 Biomuta DOID:4159 / skin cancer [ cosmic ]
S935 * Biomuta DOID:3571 / liver cancer [ cosmic ]
R1225 P1225 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1225 W1225 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R1225 Q1225 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1302 Y1302 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1306 P1306 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1315 Q1315 Biomuta DOID:363 / uterine cancer [ icgc ]
R1315 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1392 I1392 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1509 P1509 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1567 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1623 S1623 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1631 L1631 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]