iPTMnet Report for Q9UPQ7 (PDZRN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPQ7 / PZRN3_HUMAN
Protein Name E3 ubiquitin-protein ligase PDZRN3
Gene Name Name: PDZRN3
Synonyms:KIAA1095,LNX3,SEMCAP3;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPQ7
DAG View
PRO Name E3 ubiquitin-protein ligase PDZRN3 (human)
Definition An E3 ubiquitin-protein ligase PDZRN3 that is encoded in the genome of human.
Short Label hPDZRN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPQ7 (PDZRN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
S676 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
S754 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
T770 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
S837 Phosphorylation PhosphoSitePlus
S848 Phosphorylation PhosphoSitePlus
S898 Phosphorylation PhosphoSitePlus
S901 Phosphorylation PhosphoSitePlus
S910 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S955 Phosphorylation PhosphoSitePlus
T958 Phosphorylation PhosphoSitePlus
T959 Phosphorylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus
Y972 Phosphorylation PhosphoSitePlus
K1023 Acetylation PhosphoSitePlus
T1064 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T489 Phosphorylation HPRD 18452278
S774 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T249 P249 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S701 I701 Biomuta DOID:1324 / lung cancer [ cosmic ]
S750 F750 Biomuta DOID:4159 / skin cancer [ cosmic ]
S750 P750 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S778 C778 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T819 S819 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S837 I837 Biomuta DOID:3571 / liver cancer [ cosmic ]
S910 I910 Biomuta DOID:1324 / lung cancer [ cosmic ]
S915 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S955 C955 Biomuta DOID:1324 / lung cancer [ cosmic ]
T958 N958 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T959 I959 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y972 C972 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]