iPTMnet Report for Q9UPQ4 (TRIM35)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPQ4 / TRI35_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM35
Gene Name Name: TRIM35
Synonyms:HLS5,KIAA1098;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPQ4
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM35 (human)
Definition An E3 ubiquitin-protein ligase TRIM35 that is encoded in the genome of human.
Short Label hTRIM35
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPQ4 (TRIM35) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 21406692
S4 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S8 Phosphorylation PhosphoSitePlus   UniProt 21406692
K61 Ubiquitination PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
K138 Methylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
S258 O-Glycosylation GlyGen 30379171
K260 Acetylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 19007248
S8 Phosphorylation HPRD 19007248
S65 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S258 N258 Biomuta DOID:3571 / liver cancer [ cosmic ]